Cerucal Anti-Nausea/Vomiting Heartburn Migraine-50 tablet

Description

Cerucal
is an European medicine, a treatment for Nausea/Vomiting, Chemotherapy Induced, Gastroparesis that is produced by Pliva Hrvatska d.o.o., Croatia
The bottle contains 50 tablets with the
Main/Active ingredient
- Metoclopramide Hydrochloride Monohydrate (10 mg in each pill).
Excipients
: Potato Starch, Lactose Monohydrate, Gelatin, Silicon Dioxide, Magnesium Stearate.
Cerucal (Metoclopramide) is used in the treatment of:
Heartburn
Gastroparesis
GERD (Gastroesophageal Reflux Disease) Lactation Augmentation
Migraine
Nausea/Vomiting
Nausea/Vomiting, Chemotherapy Induced Nausea/Vomiting, Postoperative Radiographic Exam
Small Intestine Intubation
Anti-hiccups
How it works:
- Cerucal (Metoclopramide) increases the motility and muscle contractions of the upper gastrointestinal digestive tract, allowing faster transit of food through the GI tract and reducing symptoms such as nausea. This also speeds up the rate at which the stomach empties into the intestines.
- Experts are not sure exactly how metoclopramide exerts this effect but suggest it is due to its effects on dopamine receptors in the brain and gut.
- Cerucal (Metoclopramide) belongs to the class of medicines known as antiemetics. It may also be called a prokinetic.
Upsides:
~ Used for the short-term relief (4-12 weeks) of symptomatic gastroesophageal reflux disease that has not responded to other doctor-prescribed treatment, or to treat diabetic stasis. When used for this purpose, metoclopramide is more likely to help daytime symptoms, especially those following a meal; effect on night-time symptoms is less. May be effective when used prophylactically, such as a single dose before a meal.
~ May also be effective for people with diabetes who have problems with gastric emptying (symptoms include nausea, vomiting, heartburn, persistent fullness after meals, and weight loss).
~ Cerucal (Metoclopramide) tablets may also be used for other indications off-label.
Downsides:
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:
~ Sedation or mental impairment which may affect a person's ability to drive or operate machinery. Other side effects include restlessness, fatigue, confusion, insomnia, galactorrhea (a milky discharge from the nipples unrelated to lactation), gynecomastia (breast enlargement in males), mental depression (may include thoughts of suicide; only give to people with a history of depression if the benefits outweigh the risks).
~ May cause movement disorders (such as tremor and rigidity; a mask-like face). These are called extrapyramidal symptoms and are more common within the first 6 months of treatment. These side effects may take two to three months to subside following discontinuation. Adults aged less than 30 are more at risk.
~ Rarely, may cause Neuroleptic Malignant Syndrome; symptoms include high body temperature, muscle rigidity, and mental disturbances. Discontinue Cerucal (Metoclopramide) immediately and seek urgent medical advice.
~ Some people may experience withdrawal symptoms after stopping Cerucal (Metoclopramide), such as dizziness, nervousness, or headaches.
Bottom Line:
Cerucal (Metoclopramide) may be used short-term for the treatment of gastrointestinal reflux disease that is unresponsive to other medications, or to treat diabetic stasis. Side effects may include sedation and movement disorders such as muscle rigidity and tardive dyskinesia.
Response and Effectiveness:
Cerucal (Metoclopramide) takes about one to three minutes to start working following an intravenous dose; 10-15 minutes following an intramuscular dose; and 30-60 minutes following an oral dose. Effects last for approximately one to two hours.
Further information:
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Cerucal only for the indication prescribed.
Always consult your healthcare provider to ensure this information applies to your personal circumstances.
Dosing and Administration:
Cerucal (Metoclopramide) oral is taken for up to 12 weeks.
NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS.
Metoclopramide dosing information
Usual Adult Dose for Nausea/Vomiting:
Postoperative nausea and vomiting:
Parenteral: 10 to 20 mg IM at or near the end of surgery
Usual Adult Dose for Gastroesophageal Reflux Disease:
Oral: 10 to 15 mg up to 4 times a day 30 minutes before meals and at bedtime, depending upon symptoms being treated and clinical response. Therapy should not exceed 12 weeks.
Usual Adult Dose for Small Intestine Intubation:
If the tube has not passed the pylorus with conventional methods in 10 minutes, a single (undiluted) dose may be administered IV slowly over 1 to 2 minutes:
Adults and pediatric patients greater than or equal to 14 years: 10 mg IV as a single dose administered over 1 to 2 minutes.
Usual Adult Dose for Radiographic Exam:
Adults and pediatric patients greater than or equal to 14 years: 10 mg IV as a single dose administered over 1 to 2 minutes to facilitate gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine.
Usual Adult Dose for Gastroparesis:
During the earliest manifestations of diabetic gastric stasis, oral administration may be initiated. If severe symptoms are present, therapy should begin with IM or IV administration for up to 10 days until symptoms subside at which time the patient can be switched to oral therapy. Since diabetic gastric stasis is often recurrent, therapy should be re-instituted at the earliest manifestation.
Parenteral: 10 mg 4 times daily, IV (slowly over a 1 to 2 minute period) or IM for up to 10 days.
Oral: 10 mg 4 times daily, 30 minutes before meals and at bedtime, for 2 to 8 weeks depending on clinical response.
Usual Adult Dose for Nausea/Vomiting -- Chemotherapy Induced:
IV infusion: 1 to 2 mg/kg/dose (depending on the emetogenic potential of the agent) IV (infused over a period of not less than 15 minutes) 30 minutes before administration of chemotherapy. The dose may be repeated twice at 2 hour intervals following the initial dose. If vomiting is still not suppressed, the same dose may be repeated 3 more times at 3 hour intervals.
Usual Adult Dose for Migraine:
Use for treatment of migraine headaches is not an FDA approved indication; however, metoclopramide has shown e
ffi
cacy in studies at a dose of 10 to 20 mg IV once (used in combination with analgesics or ergot derivatives).
Usual Pediatric Dose for Gastroesophageal Reflux Disease:
Metoclopramide is not approved by the FDA for gastroesophageal reflux disease in pediatric patients; however, the following doses have been studied:
Oral, IM, IV:
Infants and Children: 0.4 to 0.8 mg/kg/day in 4 divided doses
Usual Pediatric Dose for Small Intestine Intubation:
Metoclopramide IV is approved by the FDA for pediatric use to facilitate small bowel intubation by causing gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine.
If the tube has not passed the pylorus with conventional methods in 10 minutes, a single (undiluted) dose may be administered IV slowly over 1 to 2 minutes:
Less than 6 years: 0.1 mg/kg IV as a single dose
6 to 14 years: 2.5 to 5 mg IV as a single dose
Children greater than 14 years: 10 mg as a single dose
Usual Pediatric Dose for Nausea/Vomiting -- Chemotherapy Induced:
Metoclopramide is not approved by the FDA for chemotherapy induced nausea and vomiting in pediatric patients; however, the following doses have been studied:
IV: 1 to 2 mg/kg/dose IV every 30 minutes before chemotherapy and every 2 to 4 hours
Usual Pediatric Dose for Nausea/Vomiting -- Postoperative:
Metoclopramide is not approved by the FDA for postoperative nausea and vomiting in pediatric patients; however, the following doses have been studied:
IV: Children less than or equal to 14 years: 0.1 to 0.2 mg/kg/dose (maximum dose: 10 mg/dose); repeat every 6 to 8 hours as needed
Children greater than 14 years and Adults: 10 mg; repeat every 6 to 8 hours as needed.
Storage conditions:
For tablets in bottle: Store at 15-25° C (59-77° F), protected from light. Expiration Date: May-2023
Keep out of the reach of children!
Packing: Bottle of 50 tablets, 10 mg
This product is designed and manufactured by Pliva Hrvatska d.o.o., Croatia, distributed by Teva Pharmaceutical Private Co. Ltd, Israel. Brand:
TEVA
Registration number:
N012812/01
Important:
THE DESIGN OF THE PACKAGE CAN BE DIFFERENT FROM THE ONE PROVIDED ON A PHOTO
If you have any questions, please feel free to email me first.